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Acarbose did not induce any DNA damage in vitro in the CHO chromosomal aberration assaybacterial mutagenesisAmesassayor a DNA binding assayIn vivono DNA damage was detected in the dominant lethal test in male miceor the mouse micronucleus test.
Sulfonylurea agents or insulin may cause hypoglycemiaPRECOSE given in combination with a sulfonylurea or insulin will cause a further lowering of blood glucose and may increase the potential for hypoglycemiaIf hypoglycemia occursappropriate adjustments in the dosage of these agents should be made.
Tell your doctor right away if you have any serious side effectsincludingsigns of liver problemssuch as nausea/vomiting that doesn’t stoploss of appetitestomach/abdominal painyellowing eyes/skindark urine
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if this happens to you, your doctor may recommend that generic precose be discontinued temporarily and injected insulin used instead.